Permeation Testing of Gloves with Chemotherapy Drugs & Industrial Chemicals Methods Available at ARDL Include:
Examination Gloves, Medical Gloves, Poly (Vinyl Chloride) Gloves, Protective Gloves & Surgical Gloves

ASTM D 3577
Standard Specification for Rubber Surgical Gloves (US Pharmacopeia)

ASTM D 3578
Standard Specification for Rubber Examination Gloves
ASTM D 5151
Standard Test Method for Detection of Holes in Medical Gloves
ASTM D 5250
Standard Specification for Poly(vinyl chloride) Gloves for Medical Application
ASTM D 6124
Standard Test Method for Residual Powder on Medical Gloves
ASTM D 6978
Standard Practice for Assessment of Resistance of Medical Gloves to Permeation by Chemotherapy Drugs
EN 374-2
Determination of Resistance to Water Penetration

This is the reference test specified by the European Standard for the assessment of glove quality. Gloves must pass this test in order to prove that they are an effective barrier against liquids and micro-organisms. A statistical sample taken from a batch of gloves is subject to checks for pinholes and leaks by either inflation with air or by filling with water. Performance levels are assessed according to the acceptable quality levels (AQL) of the gloves.

Gloves must meet at least level 2 of EN374-2 to be considered micro-organism resistant.
EN 374-3
Determination of Resistance to Permeation by Chemicals

Resistance to permeation is assessed by measuring the time for a chemical to breakthrough the glove material. Samples, cut from the palms of gloves, are placed in a permeation cell which enables the chemical to be placed in contact with the outer surface of the gloves. Collection air or water is passed through the cell to collect any chemical that has broken through to the inside surface of the glove sample. Polyco laboratories are equipped with a FTIR spectrometer (to detect solvents), conductivity/pH electrodes (to detect acids, alkalis and salts) and UV/Visible spectrophotometer (to detect high boiling point, water soluble chemicals and solvents).

To carry the chemical pictogram, products must now meet at least level 2 of EN 374-2 as well as a performance level 2 when tested against three of the following chemicals: Acetone, Acetonitrile, Carbon Disulphide, Diethylamine, Ethyl Acetate, Methanol, n-Heptane, Sodium Hydroxide, Sulphuric Acid (96%), Tetrahydrofuran, Toluene.
ARDL can test to additional standardized specifications as well as custom specifications. If you are interested in a method that is not listed here, please do not hesitate to call (330) 794-6600 or toll free (866) 778-ARDL to find out if we can perform your test. Chances are we can help and if not, we may know someone who can.

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