Test Methods
USP 381: Elastomeric Closures - Extraction - Total Extractables, Heavy Metals, Reducing Agents, pH Change
USP 381: Elastomeric Closures
• Absorbance
• Acidity or Alkalinity
• Ammonium
• Extraction
- Drug Vehicle
- IPA
- Purified Water
• Determination of Color
• Extractable Zinc
• Fragmentation
• Heavy Metals
• Identity Test
• Opalescence
• Penetrability
• pH Change
• Reducing Substances
• Self-Sealing Capacity
• Total Extractables
• Turbidity
• Volatile Sulfides
USP 381
